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IHS Diagnosis ICD-10
6.7.4 Headache attributed to pituitary apoplexy [E23.6] G44.81  

Diagnostic criteria:

  1. Severe acute retro-orbital, frontal or diffuse headache accompanied by at least one of the following and fulfilling criteria C and D:
    1. nausea and vomiting
    2. fever
    3. diminished level of consciousness
    4. hypopituitarism
    5. hypotension
    6. ophthalmoplegia or impaired visual acuity
  2. Neuroimaging evidence of acute haemorrhagic pituitary infarction
  3. Headache develops simultaneously with acute haemorrhagic pituitary infarction
  4. Headache and other symptoms and/or signs resolve within 1 month

Comment:

This rare clinical syndrome is an acute, life-threatening condition, characterised by spontaneous haemorrhagic infarction of the pituitary gland. It is one of the causes of thunderclap headache.

Magnetic resonance imaging is more sensitive than CT scan for detecting intrasellar pathology.

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