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5. HEADACHE ATTRIBUTED TO HEAD AND/OR NECK TRAUMA 6. HEADACHE ATTRIBUTED TO CRANIAL OR CERVICAL VASCULAR DISORDER 7. HEADACHE ATTRIBUTED TO NON-VASCULAR INTRACRANIAL DISORDER 8. HEADACHE ATTRIBUTED TO A SUBSTANCE OR ITS WITHDRAWAL 8.1. Headache induced by acute substance use or exposure  8.1.1. Nitric oxide (NO) donor-induced headache [X44]8.1.1.1. Immediate NO donor-induced headache [X44] 8.1.1.2. Delayed NO donor-induced headache [X44] 8.1.2. Phosphodiesterase (PDE) inhibitor-induced headache [X44] 8.1.3. Carbon monoxide-induced headache [X47] 8.1.4. Alcohol-induced headache [F10]8.1.4.1. Immediate alcohol-induced headache [F10] 8.1.4.2. Delayed alcohol-induced headache [F10] 8.1.5. Headache induced by food components and additives 8.1.5.1. Monosodium glutamate-induced headache [X44] 8.1.6. Cocaine-induced headache [F14] 8.1.7. Cannabis-induced headache [F12] 8.1.8. Histamine-induced headache [X44] 8.1.8.1. Immediate histamine-induced headache [X44] 8.1.8.2. Delayed histamine-induced headache [X44] 8.1.9. Calcitonin gene-related peptide (CGRP)-induced headache [X44] 8.1.9.1. Immediate CGRP-induced headache [X44] 8.1.9.2. Delayed CGRP-induced headache  [X44] 8.1.10. Headache as an acute adverse event attributed to medication used for other indications [code to specify substance] 8.1.11. Headache attributed to other acute substance use or exposure [code to specify substance] 8.2. Medication-overuse headache (MOH) 8.3. Headache as an adverse event attributed to chronic medication [code to specify substance] 8.4. Headache attributed to substance withdrawal Bibliography9. HEADACHE ATTRIBUTED TO INFECTION 10. HEADACHE ATTRIBUTED TO DISORDER OF HOMOEOSTASIS 11. HEADACHE OR FACIAL PAIN ATTRIBUTED TO DISORDER OF CRANIUM, NECK, EYES, EARS, NOSE, SINUSES, TEETH, MOUTH OR OTHER FACIAL OR CRANIAL STRUCTURES 12. HEADACHE ATTRIBUTED TO PSYCHIATRIC DISORDER 

IHS	Diagnosis	ICD-10
8.1.9	Calcitonin gene-related peptide (CGRP)-induced headache [X44]	G44.40

Comment:

The headache-inducing property of CGRP has been studied only in one double-blind controlled trial. There is, however, no doubt that CGRP causes an immediate headache. Delayed migraine attacks were induced in 3 out of 10 subjects. Recently, it has been shown that a CGRP antagonist is effective in the acute treatment of migraine.

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Consult the Sitemap to learn more about the structure of the classification and its main chapters.

IHS vs. ICD-10

To facilitate headache diagnosis in daily practice, the classification provides the corresponding WHO ICD-10NA codes for each IHS code.

IHS Subcommittee

The Classification Subcommittee prepares and revises the International Classification of Headache Disorders.

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Cephalalgia

Cephalalgia is the official journal of the IHS. It contains original papers on all aspects of headache. The journal provides an international forum for original research papers, review articles and short communications.www.cephalalgia.org

IHS Discussion Group

Ask questions and share information about the 2nd edition of the Headache Classification in one of our peer-to-peer forums. To the Discussion Group

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