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IHS Diagnosis ICD-10
8.4.3 Oestrogen-withdrawal headache [Y42.4] G44.83  

Diagnostic criteria:

  1. Headache or migraine fulfilling criteria C and D
  2. Daily use of exogenous oestrogen for ≥3 weeks, which is interrupted
  3. Headache or migraine develops within 5 days after last use of oestrogen
  4. Headache or migraine resolves within 3 days

Comment:

Oestrogen-withdrawal following cessation of a course of exogenous oestrogens (such as during the pill-free interval of combined oral contraceptives or following a course of replacement or supplementary oestrogen) can induce headache and/or migraine.

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