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IHS Diagnosis ICD-10
10.1.3 Sleep apnoea headache [G47.3] G44.882  

Diagnostic criteria:

  1. Recurrent headache with at least one of the following characteristics and fulfilling criteria C and D:
    1. occurs on >15 days per month
    2. bilateral, pressing quality and not accompanied by nausea, photophobia or phonophobia
    3. each headache resolves within 30 minutes
  2. Sleep apnoea (Respiratory Disturbance Index ≥5) demonstrated by overnight polysomnography
  3. Headache is present upon awakening
  4. Headache ceases within 72 hours, and does not recur, after effective treatment of sleep apnoea

Comments:

Although morning headache is significantly more common in patients with sleep apnoea than in the general population, headache present upon awakening is a non-specific symptom which occurs in a variety of primary and secondary headache disorders, in sleep-related respiratory disorders other than sleep apnoea (eg, Pickwickian syndrome, chronic obstructive pulmonary disorder), and in other primary sleep disorders such as periodic leg movements of sleep. A definitive diagnosis of 10.1.3 Sleep apnoea headache requires overnight polysomnography.

It is unclear whether the mechanism of 10.1.3 Sleep apnoea headache is related to hypoxia, hypercapnia or disturbance in sleep.

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