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IHS Diagnosis ICD-10
10.3.4 Headache attributed to pre-eclampsia [O13-O14] G44.813  

Diagnostic criteria:

  1. Headache with at least one of the following characteristics and fulfilling criteria C and D:
    1. bilateral
    2. pulsating quality
    3. aggravated by physical activity
  2. Pregnancy or puerperium (up to 4 weeks post-partum), and pre-eclampsia defined by both of the following:
    1. hypertension (>140/90 mm Hg) documented on two blood pressure readings at least 4 hours apart
    2. urinary protein excretion >0.3 g per 24 hours
  3. Headache develops during periods of high blood pressure
  4. Headache resolves within 7 days after effective treatment of hypertension
  5. Appropriate investigations have ruled out vasopressor toxins, medications or phaeochromocytoma as causative factors

Comment:

A placenta appears essential for the development of pre-eclampsia. Pre-eclampsia is a multi-system disorder with various forms. In addition to hypertension and proteinuria, tissue oedema, thrombocytopenia and abnormalities in liver function can occur. Pre-eclampsia appears to involve a strong maternal inflammatory response, with broad immunological systemic activity.

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