| IHS | Diagnosis | ICD-10 |
|---|---|---|
| 10.5 | Headache attributed to fasting [T73.0] | G44.882 |
| Coded elsewhere | Hypoglycaemia-induced migraine is coded according to subtype under 1. Migraine , with hypoglycaemia considered as a precipitating factor. | |
Diagnostic criteria:
- Headache with at least one of the following characteristics and fulfilling criteria C and D:
- frontal location
- diffuse pain
- non-pulsating quality
- mild or moderate intensity
- The patient has fasted for >16 hours
- Headache develops during fasting
- Headache resolves within 72 hours after resumption of food intake
Comments:
Headache with fasting is significantly more common in individuals with a prior history of headache. In those individuals with a prior history of migraine, the headache may resemble 1.1 Migraine without aura.
The likelihood of headache developing as a result of a fast increases with the duration of the fast.
The headache associated with fasting does not appear to be related to duration of sleep, to caffeine withdrawal or to hypoglycaemia. Although headache may occur under conditions of hypoglycaemia-induced brain dysfunction, there is no conclusive evidence to support a causal association. Fasting headache can occur in the absence of hypoglycaemia, insulin-induced hypoglycaemia does not precipitate headache in migraine sufferers, and headache is not a complaint of patients presenting to the emergency department with symptomatic hypoglycaemia. Well-controlled studies are needed to demonstrate a causal relationship, if one exists.

